Genetic Architecture and Signatures of Selection in the Caqueteño Creole (Colombian Native Cattle)

Evolutionary mechanisms have shaped the genomic architecture of Colombian Creole cattle breeds. The mating and selection processes impacted several traits, promoting differences within between populations. Studies population structure signatures in breeds are scarce, need more attention to better understand genetic differentiation, gene flow, distance. This study aimed analyze identify imprints Criollo Caqueteño (CAQ) population. It used 127 CAQ animals genotyped with Chip HD 777,000 SNPs. analyses discriminant principal component analysis (DAPC), integrated haplotype scoring (iHS), index-fixing (Fst) methodologies detect signals. We can highlight SNP regions on genes TMPRSS15, PGAM2, EGFR, identified by Fst method. Additionally, iHS for cluster 1 candidate BTA 3 (CMPK1 FOXD2), 11 (RCAN1), 22 (ARPP21). In group 2, we 4 (SLC13A4, BRAF), 9 (ULBP), 14 (CSMD3) 19 (KRTAP9-2). These been associated fertility precocity, growth, environmental disease resistance, indicating a potential animals. All this promotes understanding diversity Based that, our significantly assist sustainable development conservation breed Amazon.